There’s a related question, https://retrocomputing.stackexchange.com/q/634/79, which covers most approaches available to connect a 50-pin SCSI drive to a recent-ish computer.

Limiting options to a laptop means the only option to connect the drive to your computer is to use a USB-to-SCSI adapter. These aren’t manufactured any more, as far as I’m aware; but they are readily available second-hand, for rather large amounts of money. If you go down this route, there are a number of points to consider:

* USB-to-SCSI adapters provide external SCSI connectors, so you’ll need something else to connect the external SCSI connector to the internal SCSI connector on your drive — options include full-blown SCSI enclosures (which also provide power), or an adapter cable;
* you’ll need to provide power to the drive, unless you use an enclosure;
* you might also need to provide termination for the drive (see the linked question).

Another potential problem is the availability of drivers for your operating system; SCSI should mostly “just work”, but I’m not sure what the level of support for USB-to-SCSI adapters is on macOS. (While USB mass storage is pretty much SCSI over USB, that doesn’t mean USB-to-SCSI adapters are supported in the same way.)

Also, watch out for USB-to-SATA adapters marketed as SCSI adapters; they won’t fit the bill.

In the end it might be simpler to buy an older SCSI-equipped Mac, or even an older PC for which an internal SCSI host-bus adapter can be purchased cheaply. In my neck of the woods, ten-year-old PCs can be found for free, and an appropriate SCSI HBA with cable would cost around ten times less than a USB-to-SCSI adapter (without all the other paraphernalia required in the latter case), with no driver uncertainty.